The mistery of Gustave Flaubert's death: could sudden unexpected death in epilepsy be part of the context?

Arquivos de Neuro-Psiquiatria

Marly De Albuquerque¹  Carla A. Scorza¹  Ricardo M. Arida¹  Esper A. Cavalheiro¹  Fulvio A. Scorza¹ 

[1] ,Universidade Federal de São Paulo Escola Paulista de Medicina São Paulo SP ,Brasil

关键词: epilepsy;    Gustave Flaubert;    SUDEP;    seizure;    epilepsia;    Gustave Flaubert;    SUDEP;    crise epiléptica;   

DOI  :  10.1590/S0004-282X2009000300038

来源: SciELO

【 摘 要 】

Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally, potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures or transmission of epileptic activity to the heart via the autonomic nervous system potentially play a role. More than two decades ago, temporal lobe epilepsy was suggested as having been the ''nervous disease'' of Gustave Flaubert, one of the most important French novelists. In these lines, as the circumstances of his death were the subject of fabulous and mysterious speculations, we postulated in this paper that Falubert' death could be due SUDEP phenomenon.

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