Jornal Brasileiro de Patologia e Medicina Laboratorial | |
Molecular characterization of Enterobacteriaceae resistant to carbapenem antimicrobials | |
Jaciane B. Marques1  Pauline C. Bonez1  Vanessa A. Agertt1  Vanessa C. Flores1  Tanise V. Dalmolin1  Grazielle G. Rossi1  Nara Lucia F. Dal Forno1  Bianca V. Bianchini1  Caren R. Mizdal1  Fallon S. Siqueira1  Roselene A. Righi1  Bettina H. Meneghetti1  Priscila A. Trindade1  Roberto C. V. Santos1  Marli M. A. Campos1  | |
关键词: Enterobacteriaceae; carbapenemase; phenotypic methods; molecular methods; enterobactérias; carbapenemases; métodos fenotípicos; métodos moleculares; | |
DOI : 10.5935/1676-2444.20150028 | |
来源: SciELO | |
【 摘 要 】
ABSTRACT The present study aimed to genotypically and phenotypically characterize clinical isolates of carbapenem-resistant Enterobacteriaceae collected from inpatients at the University Hospital of Santa Maria, during seven months. Among the clinical isolates subjected to the modified Hodge test (MHT), 62.5% were positive, indicating possible production of carbapenemase. Polymerase chain reaction (PCR) demonstrated that blaKPC was the most frequently found gene (31%), followed by blaIMP (12.5%). Combined use of the methods is needed to identify carbapenem resistance in enterobacteria to prevent their spread and control the infections caused by these organisms.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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