Consequences of smoking during pregnancy for mother and child

Revista Brasileira de Saúde Materno Infantil

Gustavo Horacio Marin²  Liliana Delgado¹  Gustavo Sager²  Silvana Visentín²  Sebastiana Azzaro²  Mabel Tozzi² 

[1] ,Ministério de Salud de la Provincia de Buenos Aires Hospital Internazonal General de Agudos Gral San Martín Serviço de HematologíaBuenos Aires,Argentina

关键词: Pregnancy;    Smoking;    Gravidez;    Tabagismo;   

DOI  :  10.1590/S1519-38292003000200005

来源: SciELO

【 摘 要 】

OBJECTIVE: to evaluate the consequences of maternal smoking METHODS: a prospective study of 1.103 pregnant women. A survey in the state Hospital San Martin, de La Plata, Buenos Aires determined general data. Newborn and placenta data were also reported. Mother and child cord samples were obtained to determine blood elements and flow cytometry analysis of lymphocyte subsets performed. Data from smoking (S) and non-smoking (NS) groups were evaluated through relative risk, chi square and Student's t test. RESULTS: of all patients, 887 were NS and 226 said they smoked over five-cigarettes/day (S). The S group showed a higher probability of premature deliveries when compared to the NS group, with newborns weighing under 2,5kg, small in relation to gestational age, with Apgar scores at the 5th minute under six and hyaline membrane syndrome; intrauterine death risk was higher in this group who attended less medical appointments than scheduled. Umbilical cord blood analysis indicated lower reticulocyte index for S mothers, neutrophil count and CD4/CD8 ratio and increased erythroblast, eosinophil, basophil, total and CD8+T lymphocyte counts. CONCLUSIONS: data could explain the observations by other authors related to an increased incidence of allergy and infections in newborns caused by maternal smoking.

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