Endurance training induces structural and morphoquantitative changes in rat vagus nerve

Revista Brasileira de Medicina do Esporte

Eduardo Pianca¹  Walter Krause Neto¹  Tania Christina Pithon-curi¹  Eliane Florencio Gama¹  Alexandre Sabbag¹  Romeu Rodrigues De Souza¹ 

关键词: training;    running;    nerve tissue;    treinamento;    corrida;    tecido nervoso;    entrenamiento;    carrera;    tejido nervioso;   

DOI  :  10.1590/1517-869220152105143990

来源: SciELO

【 摘 要 】

ABSTRACTIntroduction:Many nervous system tissues and cells suffers positive changes when faced to exercise training. However, data on vagus nerve adaptation from exercise-induced study is absent.Objective:To analyze the effect of an endurance training on the vagus nerve morphology of rats.Methods:Wistar rats (6 months of age) were divided into two groups: control group (CG, n=8), and aerobic trained group (AT, n=8). AT was submitted to a treadmill training program of five times per week during 12 weeks. The maximum speed stipulated in the training protocol corresponded to 60% of the mean maximum intensity achieved by the group in the test of maximum effort.Results:Twelve weeks of treadmill training resulted in left ventricular hypertrophy in the AT group com-pared to CG. There was a significant increase in the area of both the myelinated and unmyelinated axons, and in the area of myelin sheath with training. The number of neurotubules and neurofilaments in myelinated fibers of aerobic trained group was significantly greater than CG (p≤0.05).Conclusion:Endurance training promoted significant increase in morphometric parameters of the vagus nerve in the same way it affect somatic nerves.

【 授权许可】

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