Determination of the antibacterial activity of crude extracts and compounds isolated from Hortia oreadica (Rutaceae) against oral pathogens

Brazilian Journal of Microbiology

Vanessa Gisele Pasqualotto Severino¹  Maria Fátima Das Graças Fernandes Da Silva¹  Rodrigo Lucarini²  Lilian Bueno Montanari²  Wilson Roberto Cunha²  Adriana Helena Chicharo Vinholis²  Carlos Henrique Gomes Martins² 

[1] ,Universidade Federal de São Carlos Departamento de Química Centro de Ciências Exatas e de TecnologiaSão Carlos SP ,Brasil

关键词: Hortia oreadica;    Rutaceae;    antibacterial activity;    MIC;    oral pathogens;    Hortia oreadica;    Rutaceae;    atividade antibacteriana;    CIM;    patógenos bucais;   

DOI  :  10.1590/S1517-83822009000300015

来源: SciELO

【 摘 要 】

Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-hexane extract and the compound dictamnine are the most active against the selected microorganisms.

【 授权许可】

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