Antimicrobial Activity of Geranium Oil against Clinical Strains of Staphylococcus aureus

Molecules

Monika Bigos¹  Małgorzata Wasiela¹  Danuta Kalemba¹ 

[1] ¹Medical and Sanitary Microbiology Department, Medical University of Lodz, Hallera Sq. 1, Lodz 90-647, Poland ²Institute of General Food Chemistry, Lodz University of Technology, Stefanowskiego Str., 4/10, Lodz 90-924, Poland

关键词: antibacterial activity;    geranium oil;    MIC;    multidrug resistant strains;    Staphylococcus aureus;   

DOI  :  10.3390/molecules170910276

来源: mdpi

【 摘 要 】

The aim of this work was to investigate the antibacterial properties of geranium oil obtained from Pelargonium graveolens Ait. (family Geraniaceae), against one standard S. aureus strain ATCC 433000 and seventy clinical S. aureus strains. The agar dilution method was used for assessment of bacterial growth inhibition at various concentrations of geranium oil. Susceptibility testing of the clinical strains to antibiotics was carried out using the disk-diffusion and E-test methods. The results of our experiment showed that the oil from P. graveolens has strong activity against all of the clinical S. aureus isolates—including multidrug resistant strains, MRSA strains and MLS_B-positive strains—exhibiting MIC values of 0.25–2.50 μL/mL.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.