Stem cells and respiratory diseases

Brazilian Archives of Biology and Technology

Soraia Carvalho Abreu¹  Tatiana Maron-gutierrez¹  Cristiane Sousa Nascimento Baez Garcia¹  Marcelo Marcos Morales¹  Patricia Rieken Macedo Rocco¹ 

[1] ,Universidade Federal do Rio de Janeiro Instituto de Biofísica Carlos Chagas Filho Laboratório de Investigação PulmonarRio de Janeiro RJ ,Brasil

关键词: Bone marrow;    fibrosis;    repair;    acute respiratory distress syndrome;    asthma;    emphysema;   

DOI  :  10.1590/S1516-89132008000700005

来源: SciELO

【 摘 要 】

Stem cells have a multitude of clinical implications in the lung. This article is a critical review that includes clinical and experimental studies of MedLine and SciElo database in the last 10 years, where we highlight the effects of stem cell therapy in acute respiratory distress syndrome or more chronic disorders such as lung fibrosis and emphysema. Although, many studies have shown the beneficial effects of stem cells in lung development, repair and remodeling; some important questions need to be answered to better understand the mechanisms that control cell division and differentiation, therefore enabling the use of cell therapy in human respiratory diseases.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License