Reliability study of the Behavioral Assessment of the Dysexecutive Syndrome adapted for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients

Revista Brasileira de Psiquiatria

Fabíola Canali²  Sonia M. D. Brucki¹  Paulo H. F. Bertolucci¹  Orlando F. A. Bueno¹ 

[1] ,Universidade Federal de São Paulo Department of Psychobiology São Paulo SP ,Brazil

关键词: Alzheimer's disease;    Executive functions;    Dementia;    Signs and symptoms;    Neuropsychological tests;    Doença de Alzheimer;    Funções executivas;    Demência;    Sinais e sintomas;    Testes neuropsicológicos;   

DOI  :  10.1590/S1516-44462011005000015

来源: SciELO

【 摘 要 】

OBJECTIVE: Ecological tests are useful in assessing executive function deficits and may be of value in appraising response to treatment in Alzheimer's disease patients. Our aims were to examine executive function using the Behavioral Assessment of the Dysexecutive Syndrome for a Brazilian sample of older-adult controls and probable early Alzheimer's disease patients, and verify the applicability of this test battery. METHOD: Forty-one older-adult controls were matched with mild Alzheimer's disease patients by age, education, and gender. RESULTS: There significant inter-group differences in overall profile and almost all subtests except temporal judgment, time spent on planning the first and second Zoo Map visit, number of errors when copying drawings, naming pictures and Six Modified Elements arithmetic, and dysexecutive questionnaire self-rating. The Behavioral Assessment of the Dysexecutive Syndrome item that best discriminated controls from patients was the Modified Six Elements - adapted (general index), with a sensitivity of 80% and specificity of 90%, (AUC = 0.91, p < 0.001). CONCLUSION: Behavioral Assessment of the Dysexecutive Syndrome was effective in detecting executive function deficits in mild Alzheimer's disease patients, particularly the task switching, time monitoring, and rule-shift subtests.

【 授权许可】

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