Erythema induratum of Bazin associated with Addison's disease: first description

Sao Paulo Medical Journal

Rodrigo Antonio Brandão Neto²  Jozélio Freire De Carvalho¹ 

[1] ,Universidade de São Paulo Faculdade de Medicina Hospital das ClínicasSão Paulo,Brazil

关键词: Addison disease;    Adrenal insufficiency;    Tuberculosis;    Erythema induratum;    Tuberculosis;    cutaneous;    Doença de Addison;    Insuficiência adrenal;    Tuberculose;    Eritema endurado;    Tuberculose cutânea;   

DOI  :  10.1590/S1516-31802012000600008

来源: SciELO

【 摘 要 】

CONTEXT: Erythema induratum of Bazin (EIB) is considered to be a tuberculid reaction and consists of recurrent painful nodules. The differential diagnosis includes diseases like nodular vasculitis, perniosis, polyarteritis nodosa and erythema nodosum. CASE REPORT: We report the case of a woman with EIB who developed Addison's disease during treatment with anti-tuberculosis drugs with good response to glucocorticoid replacement. The diagnosis was obtained through the clinical picture, positive tuberculin test and positive BCG (bacillus Calmette-Guérin) test on the histological sample. Anti-tuberculosis drugs and glucocorticoid replacement led to disappearance of the signs and symptoms. CONCLUSIONS: This is the first description of an association between EIB and Addison's disease. It should be borne in mind that tuberculosis is an important etiological factor for Addison's disease.

【 授权许可】

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