Jaboticaba (Myrciaria jaboticaba (Vell.) Berg.) peel improved triglycerides excretion and hepatic lipid peroxidation in high-fat-fed rats

Revista de Nutrição

Ângela Giovana Batista²  Sabrina Alves Lenquiste²  Carolin Moldenhauer¹  Juliana Teixeira Godoy²  Soely Maria Pissini Machado Reis²  Mário Roberto Maróstica Júnior² 

[1] ,Universidade Estadual de Campinas Faculdade de Engenharia de Alimentos Departamento de Alimentos e NutriçãoCampinas SP ,Brasil

关键词: Myrciaria jaboticaba (Vell.) Berg;    Cholesterol;    Triglycerides;    Lipid profile;    Obesity;    Myrciaria jaboticaba (Vell.) Berg;    Colesterol;    Triglicerídeos;    Perfil lipídico;    Obesidade;   

DOI  :  10.1590/S1415-52732013000500008

来源: SciELO

【 摘 要 】

OBJECTIVE: The aim of this study was to evaluate the influence of high-fat diets with 1%, 2%, and 4% freeze-dried jaboticaba peel on the serum, liver, and fecal lipid profile of obese rats. METHODS: Thirty male Sprague-Dawley rats were divided into 5 groups. Obesity was induced in four groups using a high-fat diet (35% lipids). One group was used as a high-fat diet control (High-fat group - HF). The other three high-fat-diet groups were given 1%, 2%, and 4% freeze-dried jaboticaba peel (High-Fat Jaboticaba - HFJ1, HFJ2, and HFJ4, respectively) in the last 40 experimental days. Blood and the liver were collected after 70 days of treatment and feces were collected in the last experimental week. Total cholesterol, triglycerides, and lipids were measured in the serum, liver, and dried feces. ffer in the experimental groups. HFJ2 group had the highest hepatic and fecal lipid contents compared with the group fed a diet with normal fat content (N), but low hepatic lipid peroxidation. HFJ4 group had the highest mean hepatic and fecal cholesterol levels. Hepatic triglyceride levels did not differ among the groups, and groups HFJ1 and HFJ4 presented the highest fecal triglyceride content. CONCLUSION: The amounts of jaboticaba peel used by this study did not protect against hepatic steatosis or undesired levels of other studied lipids, but it did increase fecal triglycerides. Lipid peroxidation in the liver decreased in the HFJ2 group.

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