Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil

Brazilian Journal of Infectious Diseases

Lorena C.c. Fehlberg²  Albalucia M.c. Carvalho¹  Eloiza H. Campana²  Paulo P. Gontijo-filho¹  Ana C. Gales² 

[1] ,Universidade Federal de São Paulo Laboratório Alerta, Division of Infectious Diseases São Paulo SP ,Brazil

关键词: Beta-lactam resistance;    Modified Hodge test;    Carbapenem resistance;    Enterobacteriaceae;   

DOI  :  10.1016/j.bjid.2012.07.001

来源: SciELO

【 摘 要 】

The emergence of KPC-2 producing K. pneumoniae in hospitalized patients at the intensive care unit (ICU) of a teaching hospital located in the city of João Pessoa, Paraíba, Brazil, is reported. Seven carbapenem-resistant K. pneumoniae recovered from different body sites of infection were analyzed. Most isolates showed a multidrug-resistance phenotype. Genotypic analysis demonstrated the presence of two genotypes, with the predominance of genotype A, which belongs to ST 437. These isolates also carry the encoding genes of five other betalactamases.

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