Sarcopenia of ageing: functional, structural and biochemical alterations

Brazilian Journal of Physical Therapy

S Zhong¹  Cn Chen¹  Lv Thompson¹ 

[1] ,University of MinnesotaMinneapolis Minnesota ,USA

关键词: Age;    skeletal muscle fiber;    myosin ATPase;    myofibril;    Envelhecimento;    fibra músculo esquelética;    miosina ATPase;    miofibrila;   

DOI  :  10.1590/S1413-35552007000200002

来源: SciELO

【 摘 要 】

Aging is associated with a progressive decline of muscle mass, strength, and quality, a condition described as sarcopenia of aging. Despite the significance of skeletal muscle atrophy, the mechanisms responsible for the deterioration of muscle performance are only partially understood. The purpose of this review is to highlight cellular, molecular and biochemical changes that contribute to age-related muscle weakness.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License