Light and transmission electron microscopy of generalized dystrophic epidermolysis bullosa (Pasini's albopapuloid subtype)

Anais Brasileiros de Dermatologia

Hiram Larangeira De Almeida Jr²  Lísia Nudelmann¹  Nara Moreira Rocha¹  Luis Antonio Suita De Castro¹ 

[1] ,Universidade Federal de PelotasPelotas RS ,Brazil

关键词: Epidermolysis bullosa dystrophica;    Epidermolysis bullosa;    junctional;    Epidermolysis bullosa simplex;    Histology;    Microscopy;    electron;    transmission;    Epidermólise bolhosa distrófica;    Epidermólise bolhosa juncional;    Epidermólise bolhosa simples;    Histologia;    Microscopia eletrônica de transmissão;   

DOI  :  10.1590/S0365-05962012000200014

来源: SciELO

【 摘 要 】

Pasini's albopapuloid epidermolysis bullosa is a very rare subtype of generalized dystrophic dominant epidermolyis bullosa. A 30 year-old white female patient presented since her childhood disseminated small blisters and papules. Light microscopy of a blister showed dermal-epidermal cleavage; moreover, focal areas of dermal-epidermal splitting were also observed. Transmission electron microscopy also identified focal areas of cleavage, which were seen below the lamina densa. It is important to recognize this condition as a variant of epidermolysis bullosa, since the most important cutaneous findings are generalized papules and not blisters and erosions as in other forms of epidermolysis bullosa.

【 授权许可】

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