Brazilian Dental Journal | |
Assessment of Bone Healing in Rabbit Calvaria Grafted with Three Different Biomaterials | |
Carlos Alberto Yoshihiro Takauti1  Fabio Futema1  Rui Barbosa De Brito Junior1  Aline Corrêa Abrahão1  Claudio Costa1  Celso Silva Queiroz1  | |
关键词: biomaterials; bone regeneration; xenogen bovine graft; alloplastic graft.; | |
DOI : 10.1590/0103-6440201302383 | |
来源: SciELO | |
【 摘 要 】
This study evaluated the bone regeneration process in rabbit calvaria induced by three types of biomaterials: two xenogenous, consisting of deproteinized bovine bone, while the other was alloplastic, based on biphasic calcium phosphate. Five New Zealand white rabbits weighing between 2,900 and 3,500 g were submitted to four standard 8 mm-diameter perforations at the parietal bone. Three perforations were filled with three grafts and biomaterials, two of them received bovine Bio-Oss(r) and Endobon(r) Xenograft Granules, and the other consisted of fully alloplastic Straumann(r) Bone Ceramic. The fourth remaining cavity was used as control with coagulum. After eight weeks, the animals were sacrificed, and the samples were prepared for morphometric and qualitative analysis. The cavities filled with alloplastic biomaterials showed higher percentages of newly formed bone (p<0.05), while the cavities with xenogenous biomaterials showed higher amount of residual graft (p<0.05). Although the results showed greater bone formation with Straumann(r) Bone Ceramic, further studies are required to prove which is the more effective biomaterial for bone induction process.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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