New phenolic glycosides from Phyllanthus cochinchinensis

Journal of the Brazilian Chemical Society

Jian-qiang Zhao¹  Yan-ming Wang¹  Jun-jiang Lv¹  Hong-tao Zhu¹  Dong Wang¹  Chong-ren Yang¹  Min Xu¹  Ying-jun Zhang¹ 

[1] ,Chinese Academy of Sciences Kunming Institute of Botany Plant Resources in West ChinaKunming,P. R. China

关键词: Phyllantus cochinchinensis;    Euphorbiaceae;    phenolic glycosides;    cytotoxicity;    antimicrobial activity;   

DOI  :  10.5935/0103-5053.20140127

来源: SciELO

【 摘 要 】

Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.

【 授权许可】

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