Regiospecific synthesis of new fatty N-acyl trihalomethylated pyrazoline derivatives from fatty acid methyl esters (FAMEs)

Journal of the Brazilian Chemical Society

Paulo Beck²  Juliane M. Dos Santos²  Bruna L. Kuhn¹  Dayse N. Moreira¹  Alex F. C. Flores¹  Marcos A. P. Martins¹  Marcelo G. M. D'oca²  Luciana A. Piovesan² 

[1] ,Universidade Federal do Rio Grande Escola de Química e Alimentos Rio Grande RS ,Brazil

关键词: N-acyl hydrazine;    FAMEs;    4-alkoxy-1;    1;    1-trialomethyl-3-alquen-2-ones;    N-acyl trialomethylated pyrazoline;   

DOI  :  10.1590/S0103-50532012005000071

来源: SciELO

【 摘 要 】

A series of new fatty N-acyl trihalomethylated pyrazoline derivatives from fatty acid methyl esters was synthesized by the cyclocondensation of respective fatty hydrazides with 4-alkoxy-1,1,1-trialomethyl-3-alquen-2-ones. Efficient and regiospecific cyclizations catalyzed by BF3·MeOH gave the desired products in good to excellent yields and at high purity.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License