Palladium catalyzed Suzuki cross-coupling of 3-iodo-2-(methylthio)-benzo[b]furan derivatives: synthesis of 3-aryl-2-(methylthio)benzo[b]furans

Journal of the Brazilian Chemical Society

Rafaela M Gay¹  Flávia Manarin¹  Ricardo Brandão¹  Gilson Zeni¹ 

[1] ,Universidade Federal de Santa Maria Centro de Ciências Naturais e Exatas Departamento de QuímicaSanta Maria RS ,Brazil

关键词: palladium;    Suzuki cross-coupling;    benzofuran;    boronic acids;   

DOI  :  10.1590/S0103-50532010000900006

来源: SciELO

【 摘 要 】

A selective and efficient method for the synthesis of 3-aryl-2-(methylthio)benzo[b]furans derivatives by palladium catalyzed cross-coupling reaction with boronic acids has been developed. The reaction proceeded cleanly under mild conditions and was performed with aryl boronic acids bearing electron-withdrawing, electron donating and neutral substituents.

【 授权许可】

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