Palladium catalyzed Suzuki cross-coupling of 3-iodo-2-(methylthio)-benzo[b]furan derivatives: synthesis of 3-aryl-2-(methylthio)benzo[b]furans

Journal of the Brazilian Chemical Society

Brandão, Ricardo¹  Gay, Rafaela M¹  Manarin, Flávia¹  Zeni, Gilson¹  Universidade Federal de Santa Maria, Santa Maria, Brazil¹ 

关键词: palladium;    Suzuki cross-coupling;    benzofuran;    boronic acids;   

DOI  :  10.1590/S0103-50532010000900006

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

A selective and efficient method for the synthesis of 3-aryl-2-(methylthio)benzo[b]furans derivatives by palladium catalyzed cross-coupling reaction with boronic acids has been developed. The reaction proceeded cleanly under mild conditions and was performed with aryl boronic acids bearing electron-withdrawing, electron donating and neutral substituents.

【 授权许可】

Unknown