Synthesis of a Functionalized Benzofuran as a Synthon for Salvianolic Acid C Analogues as Potential LDL Antioxidants

Molecules

Gabriela López-Fr໚s¹  Alejandro A. Camacho-Dávila²  David Chávez-Flores¹  Gerardo Zaragoza-Galán¹  Vໜtor H. Ramos-Sánchez¹ 

[1] Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Circuito Universitario, Campus Universitario #2, Apartado Postal 669, Chihuahua, Chih. 31125, Mexico;

关键词: benzofuran;    antioxidant;    palladium;   

DOI  :  10.3390/molecules20058654

来源: mdpi

【 摘 要 】

A palladium mediated synthesis of a common synthon for the syntheses of antioxidant analogues of naturally occurring salvianolic acids is presented. The synthetic route may be used to obtain analogues with a balanced lipophilicity/hydrophilicity which may result in potentially interesting LDL antioxidants for the prevention of cardiovascular diseases.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.