The use of anhydrous CeCl3 as a recyclable and selective catalyst for the acetalization of aldehydes and ketones

Journal of the Brazilian Chemical Society

Claudio C. Silveira²  Samuel R. Mendes²  Francieli I. Ziembowicz²  Eder J. Lenardão¹  Gelson Perin¹ 

[1] ,Universidade Federal de Santa Maria Departamento de Química Santa Maria RS ,Brazil

关键词: cerium(III) chloride;    acetals;    trimethyl orthoformate;    aldehydes;    ketones;   

DOI  :  10.1590/S0103-50532010000200026

来源: SciELO

【 摘 要 】

An efficient, clean, chemoselective and solvent-free method for the synthesis of ketone and aldehyde dimethyl acetals was developed using trimethyl orthoformate and commercially available anhydrous CeCl3 as a recyclable catalyst. The method is general and affords the protected carbonyl compounds in good yields and under mild conditions, including aryl and alkyl ketones and activated aldehydes. The catalyst could be utilised directly for 3 cycles, without significant loss of activity.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License