The use of anhydrous CeCl3 as a recyclable and selective catalyst for the acetalization of aldehydes and ketones

Journal of the Brazilian Chemical Society

Lenardão, Eder J.¹  Silveira, Claudio C.¹  Mendes, Samuel R.¹  Universidade Federal de Pelotas, Pelotas, Brazil¹  Perin, Gelson¹  Ziembowicz, Francieli I.¹  Universidade Federal de Santa Maria, Santa Maria, Brazil¹ 

关键词: cerium(III) chloride;    acetals;    trimethyl orthoformate;    aldehydes;    ketones;   

DOI  :  10.1590/S0103-50532010000200026

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

An efficient, clean, chemoselective and solvent-free method for the synthesis of ketone and aldehyde dimethyl acetals was developed using trimethyl orthoformate and commercially available anhydrous CeCl3 as a recyclable catalyst. The method is general and affords the protected carbonyl compounds in good yields and under mild conditions, including aryl and alkyl ketones and activated aldehydes. The catalyst could be utilised directly for 3 cycles, without significant loss of activity.

【 授权许可】

Unknown