Regiospecific synthesis of 1,2-bis(azolyl)ethanes

Journal of the Brazilian Chemical Society

Marcos A. P. Martins²  Wilson Cunico²  Geonir M. Siqueira¹  Victor L. Leidens²  Nilo Zanatta²  Helio G. Bonacorso²  Alex F. C. Flores² 

[1] ,Universidade Federal de Santa Maria Departamento de Quimica Santa Maria RS ,Brazil

关键词: bis(azolyl)ethanes;    pyrazoles;    isoxazoles;    enones;   

DOI  :  10.1590/S0103-50532005000200022

来源: SciELO

【 摘 要 】

The synthesis of 1,2-bis(5'-trihalomethylisoxazol-3'-yl)ethanes (3-6) and 1,2-bis(5'-trihalomethylpyrazol-3'-yl)ethanes (7-10) from the cyclocondensation of 1,1,1,10,10,10-hexahalo-4,7-dimethoxydeca-3,7-dien-2,9-diones (1 and 2) with hydroxylamine and hydrazines is reported. In addition, the one-pot synthesis of 1,2-bis(5'-alkoxycarbonylpyrazol-3'-yl)ethanes (11-14) by reaction of chloro-substituted dienone 2 and hydrazines is also described.

【 授权许可】

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