Regiospecific synthesis of 1,2-bis(azolyl)ethanes

Journal of the Brazilian Chemical Society

Flores, Alex F. C.¹  Universidade Federal de Pelotas, Pelotas, Brazil¹  Zanatta, Nilo¹  Siqueira, Geonir M.¹  Leidens, Victor L.¹  Bonacorso, Helio G.¹  Martins, Marcos A. P.¹  Cunico, Wilson¹  Universidade Federal de Santa Maria, Santa Maria, Brazil¹ 

关键词: bis(azolyl)ethanes;    pyrazoles;    isoxazoles;    enones;   

DOI  :  10.1590/S0103-50532005000200022

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The synthesis of 1,2-bis(5'-trihalomethylisoxazol-3'-yl)ethanes (3-6) and 1,2-bis(5'-trihalomethylpyrazol-3'-yl)ethanes (7-10) from the cyclocondensation of 1,1,1,10,10,10-hexahalo-4,7-dimethoxydeca-3,7-dien-2,9-diones (1 and 2) with hydroxylamine and hydrazines is reported. In addition, the one-pot synthesis of 1,2-bis(5'-alkoxycarbonylpyrazol-3'-yl)ethanes (11-14) by reaction of chloro-substituted dienone 2 and hydrazines is also described.

【 授权许可】

Unknown