Eletrophysiological study of the caudal nerve on developing rats

Acta Cirurgica Brasileira

Juliana Netto Maia²  Celina Cordeiro De Carvalho¹  Marina Hazin Galvão¹  Anderson De Lima Silva¹  Ana Carine Gouveia Mendes¹  Sílvia Regina Arruda De Moraes¹  Otávio Gomes Lins¹ 

[1] ,UFPE Neuropsychiatry and Behavioural Sciences Pernambuco Brazil

关键词: Neural Conduction;    Electrodiagnosis;    Rats;    Condução Nervosa;    Eletrodiagnóstico;    Ratos;   

DOI  :  10.1590/S0102-86502010000200004

来源: SciELO

【 摘 要 】

PURPOSE: To non-invasively study the sensory nerve conduction of the caudal nerve of normal developing rats. METHODS: Twenty normal Wistar male rats served as subjects. Caudal nerve conduction studies were performed at 60 days from birth and weekly at end of six consecutive weeks. The caudal nerve was stimulated distally and nerve potentials were recorded proximally on the animal's tail using common "alligator" clips as surface electrodes. RESULTS: The amplitude and the conduction velocity of the caudal nerve sensory action potential increased linearly from 29±6 µV to 85±13 µV and from 34±3 m/s to 44±4 m/s, respectively, between the 8th and the 15th week of life. The equations of linear regressions were as followed: Amplitude (µV) = 8.1 × weeks - 34 (R² = 0.99) and NCV (m/s) = 1.2 × weeks + 25 (R² = 0.86). CONCLUSIONS: It was possible to study non-invasively the sensitive conduction of the caudal nerve of normal developing rats and describe reference values. The technique and data may be used as animal model in physiological and pathological studies.

【 授权许可】

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