Nitrous Oxide Induced Subacute Combined Degeneration

Journal of Case Reports

article

Huimin Zhao¹  Zhongmin We¹  Suzhou¹  Yingying Xu¹ 

[1] Department of Neurology, The Second Affiliate Hospital of Soochow University

关键词: Demyelinating Diseases;    Magnetic Resonance Imaging;    Neural Conduction;    Nitrous Oxide;    Vitamin B12.;   

DOI  :  10.17659/01.2019.0053

学科分类：生理学

来源: Journal of Case Reports

【 摘 要 】

Background: Nitrous oxide (N2O), due to its euphoriant properties is often abused for recreational purpose. Case Report: A 38-year-old male who admitted to inhaling recreational nitrous oxide more than five months, presented with a progressive symmetrical tingling sensations and weakness of limbs. Serum vitamin B12 was lower than normal. Magnetic resonance imaging (MRI) of the spine demonstrated hyper-intensity of the posterior cord extending from C1-C5. Nerve conduction velocity test showed slowed motor conduction velocities and delayed or absent F-waves consistent with demyelinating neuropathy. The patient was managed with B12 supplement and his nerve function basically returned to normal after three months. Conclusion: This is a rare case of subacute combing degeneration caused by excessive inhalation of nitrous oxide.

【 授权许可】

Unknown