Acta Cirurgica Brasileira | |
Cardiocirculatory changes in hemorrhagic shock induced in pigs submitted to three distinct therapeutic methods | |
Gilberto Fernandes Silva De Abreu2  Antônio Roberto Barros Coelho2  José Lamartine De Andrade Aguiar2  Sílvio Amorim Moura Filho1  | |
[1] ,UFPE Department of Surgery Recife PE ,Brazil | |
关键词: Shock; Hemorrhagic; Trauma; Swine; Choque Hemorrágico; Trauma; Suínos; | |
DOI : 10.1590/S0102-86502010000100025 | |
来源: SciELO | |
【 摘 要 】
PURPOSE: To evaluate and compare the response of pigs submitted to hemorrhagic shock and treated using three different strategies. METHODS: Thirty-five Dalland pigs were divided into four groups: Control; Bleeding; Saline and Saline + Red Cell Concentrate. Parameters evaluated: heart rate (HR), mean arterial blood pressure (MAP) and central vein pressure (CVP).Hemorrhagic shock was induced by removing (624.25±64.55), (619.30±44.94) and (664.23±39.96) ml of blood respectively, with the following treatment: Bleeding Group - zero volume replacement; Saline Group - replacement with 676 ml of 0.9% saline solution; Saline + Red Cell Concentrate Group - replacement with 440 ml of 0.9% saline solution + 291 ml of red cell concentrate. The treatment was evaluated after 10 (T3), 30 (T4), 45 (T5) and 60 (T6) minutes. RESULTS: HR: No statistically significant difference was found between the Bleeding and Saline [p=1.000], Bleeding and Saline + Red Cell Concentrate [p=1.000], and Saline and Saline + Red Cell Concentrate [p=0.721] groups. MAP; Significant differences were found between all the groups studied. CVP: No significant difference was found between the groups. CONCLUSION: Non-replacement and euvolemic resuscitation maintained a satisfactory hemodynamic pattern in controlled severe hemorrhagic shock in swine. The euvolemic replacement strategies exceeded the limit values of MAP for rebleeding.
【 授权许可】
CC BY
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