Acta Cirurgica Brasileira | |
New quantitative variables to measure postoperative pericardial adhesions: useful tools in experimental research | |
Jackson Brandão Lopes2  Luís Alberto Oliveira Dallan1  Luiz Felipe Pinho Moreira1  Mário Castro Carreiro1  Flávia Luana Barbosa Rodrigues1  Pedro De Castro Mendes1  Noedir Antônio Groppo Stolf1  | |
[1] ,USP School of Medicine Heart InstituteSao Paulo,Brazil | |
关键词: Pericardium; Adhesions; Models; Animal; Random Allocation; Statistics; Nonparametric; Thoracic Surgery; Collagen; Swine; Pericárdio; Aderências; Modelos Animais; Distribuição Aleatória; Estatísticas não Paramétricas; Cirurgia Torácica; Colágeno; Suínos; | |
DOI : 10.1590/S0102-86502009000200002 | |
来源: SciELO | |
【 摘 要 】
PURPOSE: To improve the measurement system, during a research for the prevention of adhesions, we explored the feasibility of introducing three continuous numeric variables to quantify the intensity of pericardial adhesions. METHODS: To validate these three new numeric variables - time spent to dissect the adhesions (Δt), the amount of sharp dissection (ShpD) and the adhesion's collagen area (ACA) - as useful tools in measuring the severity of pericardial adhesions, data from a randomized study on adhesion prevention enrolling twenty-four swine, were analysed. A statistical Spearman's test and regressions models were applied to verify the correlation and the relationship between the results of a standard severity score (SS) and Δt, between SS and ShpD used in adhesiolysis and, also, between SS and ACA. RESULTS: There was a statistically significant correlation between SS and Δt, between SS and ShpD, as well as between SS and ACA, all measured by the Spearman's test (r=0.897, r=0.932, r=0.66; p<0.01, respectively). Through a non-linear regression, an exponential relation of SS with ShpD (R²=0.915) and SS with Δt (R²= 0.917) was found. CONCLUSION: The time spent to dissect the adhesions (Δt) and the amount of sharp dissection (ShpD) are new powerful measurement tools in evaluating outcomes of the methods used to prevent pericardial adhesions.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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