Experimental model of cranially pedicled TRAM flap in rats

Acta Cirurgica Brasileira

Elvio Bueno Garcia²  Lydia Masako Ferreira¹  Miguel Sabino Neto¹  Natasha Sallum² 

[1] ,Federal University of São Paulo EPM

关键词: Rats;    TRAM flap;    Tissue Survival;    Models;    Animal;    Ratos;    Retalho TRAM;    Modelos Animais;    Sobrevivência tecidual;   

DOI  :  10.1590/S0102-86502004000700011

来源: SciELO

【 摘 要 】

In a simple, reproducible, and non-expensive experimental model the transverse rectus abdominis muscle (TRAM) flap has been described in male, adult Wistar rats (Rattus norvegicus albinus, Rodentia, Mammalia), weighing approximately 300g, at the central biotery of the Federal University at São Paulo, Paulista Medical School (UNIFESP - EPM). This article describes the use of a cranially based pedicled rectus abdominis muscle flap sling, unilaterally to the right, with the purpose to better understand the pathophysiology of and the research on new treatments to prevent partial or total flap necrosis. This experimental model sponsors quite a number of studies to be conducted to assess the effects of different drugs of physical methods on the feasibility of standard, cranial monopedicled TRAM.As a standard model, it also harbors the comparison among results from different studies.

【 授权许可】

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