Skeletal muscle ischemia and reperfusion in rats increase lipid peroxidation in rats

Acta Cirurgica Brasileira

Carlos Eli Piccinato²  Armando De Domenico Jr²  Alceu Afonso Jordão Jr¹  Helio Vannucchi¹ 

[1] ,University of São Paulo Faculty of Medicine of Ribeirão Preto Department of Surgery and Anatomy

关键词: Ischemia;    Skeletal muscle;    Vitamin E;    Free radicals;    Rats;    Isquemia;    Músculo esquelético;    Vitamina E;    Radicais livres;    Ratos;   

DOI  :  10.1590/S0102-86502004000500018

来源: SciELO

【 摘 要 】

PURPOSE: To determine the effects of 30 minutes of ischemia followed by 30 minutes of reperfusion in skeletal muscle of rats receiving three different diets (supplemented, normal and vitamin E deficient) on lipoperoxidation (LP). METHODS: LP measured by TBARS levels, and plasma and hepatic concentrations of vitamin E measured by HPLC. RESULTS: The deficient group presented higher lipoperoxidation levels in muscle compared to the control and supplemented groups. CONCLUSION: Supplementation with vitamin E decrease the free radicals production in ischemia/reperfusion in skeletal muscle of rats.

【 授权许可】

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