Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract

Revista Brasileira de Farmacognosia

Susana Gorzalczany²  Valeria Sülsen²  Flavia Redko²  Cristina Vescina¹  Liliana Muschietti²  Virginia Martino²  Cristina Acevedo² 

[1] ,Universidad de Buenos Aires Facultad de Farmacia y Bioquímica Cátedra de FarmacologíaBuenos Aires,Argentina

关键词: Lippia integrifolia;    Verbenaceae;    choleretic effect;    antispasmodic effect;    Lippia integrifolia;    Verbenaceae;    efeito colerético;    efeito antiespasmódico;   

DOI  :  10.1590/S0102-695X2008000100005

来源: SciELO

【 摘 要 】

The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.

【 授权许可】

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