Choleretic and antispasmodic effects of Lippia integrifolia aqueous extract

Revista Brasileira de Farmacognosia

Sülsen, Valeria¹  Vescina, Cristina¹  Gorzalczany, Susana¹  Universidad de Buenos Aires, Buenos Aires, Argentina¹  Muschietti, Liliana¹  Redko, Flavia¹  Acevedo, Cristina¹  Martino, Virginia¹ 

关键词: Lippia integrifolia;    Verbenaceae;    choleretic effect;    antispasmodic effect.;   

DOI  :  10.1590/S0102-695X2008000100005

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

The aqueous extract of the aerial parts of Lippia integrifolia has been assayed for its choleretic and antispasmodic effects. Doses of 250, 500 and 750 mg/kg administered orally in rats significantly increased the bile flow and the bile acid output. The extract also showed a significant reduction of the contractions induced by acetylcholine, CaCl2 and KCl on isolated rat jejunum. The total caffeoyl quinic acids derivatives content, expressed as chlorogenic acid was 0.10% w/v by spectrophotometric determination.

【 授权许可】

Unknown