Dietary polydextrose increases calcium absorption in normal rats

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

Elisvânia Freitas Dos Santos²  Kathia Hitomi Tsuboi²  Marina Rachel Araújo¹  Arthur C. Ouwehand¹  Nelson Adami Andreollo¹  Celio Kenji Miyasaka² 

[1] ,Faculdade de Engenharia de Alimentos

关键词: Prebiotics;    Polydextrose;    Gastrectomy;    Calcium;    Rat;    Prebióticos;    Polidextrose;    Gastrectomia;    Cálcio;    Rato;   

DOI  :  10.1590/S0102-67202009000400004

来源: SciELO

【 摘 要 】

BACKGROUND: Gastric surgery is known to cause bone disorders, possibly related to an impaired capacity for the absorption of dietary calcium. AIM: To verify if polydextrose (PDX) could stimulate calcium absorption in partially gastrectomized and sham operated rats. METHODS: The rats were laparotomized (sham-operated control) or partially gastrectomized (Billroth II), in groups of 20 each. Half in each operated group were fed a control diet (AIN-93M) without PDX or the same diet containing (PDX 50g/Kg of diet) for eight weeks. The rats were divided into four subgroups: sham-operated and gastrectomized without PDX; sham-operated and gastrectomized with PDX. On the final day of the study, total blood was collected for determination of serum calcium concentration. RESULTS: In the diet with PDX, excretion of calcium in the feces was significantly lower than in the groups not receiving PDX, irrespective of the operation. Apparent calcium absorption and serum calcium was higher in the sham operated PDX fed group than in the control group. In sham operated rats, the calcium concentration in bone was higher in the PDX fed group. CONCLUSION: The polydextrose feeding increased calcium absorption and bone calcium concentration in normal rats, which may be relevant for decreasing the risk of osteoporosis. Partially gastrectomy did not affect the bone calcium concentration in 56 days of experimental period.

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