Determinação de hormônios estrógenos em água potável usando CLAE-DAD

Química Nova

Raphael Teixeira Verbinnen²  Gilvanda Silva Nunes²  Eny Maria Vieira¹ 

[1] ,Universidade Federal do Maranhão Centro de Ciências Exatas e Tecnologia Departamento de Tecnologia QuímicaSão Luís MA ,Brasil

关键词: estrogen hormones;    HPLC-DAD;    water supply;   

DOI  :  10.1590/S0100-40422010000900003

来源: SciELO

【 摘 要 】

An analytical procedure for determination of estriol, 17β-estradiol, estrone and 17α-ethinylestradiol in drinking water is presented. The method employs solid phase extraction (SPE) and sample dechlorination as cleanup procedures, followed by HPLC-DAD analysis. Validation was carried out using RE No. 899/2003 guidelines established by the Agência Nacional de Vigilância Sanitária (National Agency of Sanitary Surveillance, Brazil), with some adaptations. The statistically evaluated results have shown that the method is selective, precise (0,06% to 19,40% CV) and accurate (91,52% to 109,41% average recoveries). The developed method was applied to the analysis of these contaminants in drinking water from São Luís, MA.

【 授权许可】

CC BY-NC   
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