Determination of estrogens in drinking water using HPLC-DAD

Química Nova

Vieira, Eny Maria¹  Universidade de São Paulo, São Carlos, Brasil¹  Verbinnen, Raphael Teixeira¹  Universidade Federal do Maranhão, São Luís, Brasil¹  Nunes, Gilvanda Silva¹ 

关键词: estrogen hormones;    HPLC-DAD;    water supply.;   

DOI  :  10.1590/S0100-40422010000900003

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

An analytical procedure for determination of estriol, 17β-estradiol, estrone and 17α-ethinylestradiol in drinking water is presented. The method employs solid phase extraction (SPE) and sample dechlorination as cleanup procedures, followed by HPLC-DAD analysis. Validation was carried out using RE No. 899/2003 guidelines established by the Agência Nacional de Vigilância Sanitária (National Agency of Sanitary Surveillance, Brazil), with some adaptations. The statistically evaluated results have shown that the method is selective, precise (0,06% to 19,40% CV) and accurate (91,52% to 109,41% average recoveries). The developed method was applied to the analysis of these contaminants in drinking water from São Luís, MA.

【 授权许可】

Unknown