Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil

Memórias do Instituto Oswaldo Cruz

Paulo Victor Pereira Baio²  Higor Franceschi Mota²  Andréa D'avila Freitas²  Débora Leandro Rama Gomes²  Juliana Nunes Ramos²  Lincoln Oliveira Sant'anna²  Mônica Cristina Souza²  Thereza Cristina Ferreira Camello²  Raphael Hirata Junior²  Verônica Viana Vieira¹  Ana Luíza Mattos-guaraldi² 

[1] ,Universidade do Estado do Rio de Janeiro Hospital Universitário Pedro Ernesto Faculdade de Ciências MédicasRio de Janeiro RJ ,Brasil

关键词: Corynebacterium striatum;    nosocomial outbreak;    PFGE;    multidrug-resistant clones;   

DOI  :  10.1590/S0074-02762013000100004

来源: SciELO

【 摘 要 】

Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were 50 years of age and older). C. striatum was mostly isolated in pure culture from tracheal aspirates of patients undergoing endotracheal intubation procedures. The analysis by pulsed-field gel electrophoresis (PFGE) indicated the presence of four PFGE profiles, including two related clones of MDR strains (PFGE I and II). The data demonstrated the predominance of PFGE type I, comprising 11 MDR isolates that were mostly isolated from intensive care units and surgical wards. A potential causal link between death and MDR C. striatum (PFGE types I and II) infection was observed in five cases.

【 授权许可】

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