Memórias do Instituto Oswaldo Cruz | |
Biofilm production by multiresistant Corynebacterium striatumassociated with nosocomial outbreak | |
Cassius De Souza1  Yuri Vieira Faria1  Lincoln De Oliveira Sant’anna1  Vanilda Gonçalves Viana1  Sérgio Henrique Seabra1  Mônica Cristina De Souza1  Verônica Viana Vieira1  Raphael Hirata Júnior1  Lílian De Oliveira Moreira1  Ana Luíza De Mattos-guaraldi1  | |
关键词: biofilm; Corynebacterium striatum; epidemic clone; fibrinogen; multi-resistance; nosocomial outbreak; | |
DOI : 10.1590/0074-02760140373 | |
来源: SciELO | |
【 摘 要 】
Corynebacterium striatum is a potentially pathogenic microorganism that causes nosocomial outbreaks. However, little is known about its virulence factors that may contribute to healthcare-associated infections (HAIs). We investigated the biofilm production on abiotic surfaces of multidrug-resistant (MDR) and multidrug-susceptible (MDS) strains of C. striatum of pulsed-field gel electrophoresis types I-MDR, II-MDR, III-MDS and IV-MDS isolated during a nosocomial outbreak in Rio de Janeiro, Brazil. The results showed that C. striatum was able to adhere to hydrophilic and hydrophobic abiotic surfaces. The C. striatum1987/I-MDR strain, predominantly isolated from patients undergoing endotracheal intubation procedures, showed the greatest ability to adhere to all surfaces. C. striatumbound fibrinogen to its surface, which contributed to biofilm formation. Scanning electron microscopy showed the production of mature biofilms on polyurethane catheters by all pulsotypes. In conclusion, biofilm production may contribute to the establishment of HAIs caused by C. striatum.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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