Serological Evidence of HTLV-I and HTLV-II Coinfections in HIV-1 Positive Patients in Belém, State of Pará, Brazil

Memórias do Instituto Oswaldo Cruz

Acr Vallinoto²  Vn Azevedo²  Dem Santos²  S Caniceiro²  Fcl Mesquita¹  Ww Hall¹  Mog Ishak²  R Ishak² 

[1],Universidade Federal do Pará

关键词: HIV;    HTLV;    coinfection;    retrovirus;   

DOI  :  10.1590/S0074-02761998000300026

来源: SciELO

【 摘 要 】

The occurrence of HTLV-I/II and HIV-1 coinfections have been shown to be frequent, probably in consequence of their similar modes of transmission. This paper presents the prevalence of coinfection of HTLV among HIV-1 infected and AIDS patients in Belém, State of Pará, Brazil. A group of 149 patients attending the AIDS Reference Unit of the State Department of Health was tested for the presence of antibodies to HTLV-I/II using an enzyme immunoassay and the positive reactions were confirmed with a Western blot that discriminates between HTLV-I and HTLV-II infections. Four patients (2.7%) were positive to HTLV-I, seven (4.7%) to HTLV-II and one (0.7%) showed an indeterminate pattern of reaction. The present results show for the first time in Belém not only the occurrence of HTLV-II/HIV-1 coinfections but also a higher prevalence of HTLV-II in relation to HTLV-I. Furthermore, it also enlarges the geographical limits of the endemic area for HTLV-II in the Amazon region of Brazil.

【 授权许可】

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