Compositional Constraints in the Extremely GC-poor Genome of Plasmodium falciparum

Memórias do Instituto Oswaldo Cruz

Héctor Musto²  Simone Cacciò¹  Helena Rodríguez-maseda¹  Giorgio Bernardi¹ 

[1] ,Facultad de Ciencias

关键词: Plasmodium falciparum;    GC levels;    dinucleotides;    genome organization;   

DOI  :  10.1590/S0074-02761997000600020

来源: SciELO

【 摘 要 】

We have analyzed the compositional properties of coding (protein encoding) and non-coding sequences of Plasmodium falciparum, a unicellular parasite characterized by an extremely AT-rich genome. GC% levels, base and dinucleotide frequencies were studied. We found that among the various factors that contribute to the properties of the sequences analyzed, the most relevant are the compositional constraints which operate on the whole genome

【 授权许可】

CC BY   
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