Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction

Revista da Sociedade Brasileira de Medicina Tropical

Luna Azulay-abulafia¹  Maria Auxiliadora Jeunon Sousa¹  Andrea Pussanti¹  Daniel Dal'asta Coimbra¹  Hernando Vega¹  Fred Bernardes Filho¹ 

关键词: Aspergillosis;    Aspergillus flavus;    Rhinosinusitis;    Cocaine addiction;   

DOI  :  10.1590/0037-8682-0086-2014

来源: SciELO

【 摘 要 】

Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License