Invasive aspergillosis in a user of inhaled cocaine: rhinosinusitis with bone and cartilage destruction

Revista da Sociedade Brasileira de Medicina Tropical

Corporación Universitaria Rafael Nunez de Cartagena, Cartagena, Colombia¹  Sousa, Maria Auxiliadora Jeunon¹  Santa Casa de Misericórdia do Rio de Janeiro, Rio de Janeiro, Brasil.¹  Clínica Privada, Rio de Janeiro, Brasil.¹  Azulay-Abulafia, Luna¹  Pussanti, Andrea¹  Coimbra, Daniel Dal'Asta¹  Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil.¹  Vega, Hernando¹  Bernardes Filho, Fred¹ 

关键词: Aspergillosis;    Aspergillus flavus;    Rhinosinusitis;    Cocaine addiction;   

DOI  :  10.1590/0037-8682-0086-2014

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Aspergillosis is an infection caused by saprophytic fungi of the genus Aspergillus, which typically occurs in immunosuppressed individuals, but has also been reported in immunocompetent patients. The main routes of entry are the respiratory tract, skin, cornea, and ear, and the infection may be localized or disseminated by contiguity or vascular invasion. We report a severe case of rhinosinusitis with cutaneous involvement, caused by invasive aspergillosis, in an immunocompetent user of inhaled cocaine. Invasive aspergillosis related to cocaine abuse has not yet been reported in the literature. After itraconazole treatment and surgical debridement, complete clinical remission was achieved. Nasal reconstruction with a skin graft over a silicone prosthesis resulted in a satisfactory esthetic outcome.Key words: Aspergillosis; Aspergillus flavus; Rhinosinusitis; Cocaine addiction

【 授权许可】

Unknown