Revista da Sociedade Brasileira de Medicina Tropical | |
Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study | |
Glauco Danielle Fagundes2  Fábio De Oliveira Tabalipa1  Jane Da Silva1  | |
[1] ,Universidade do Extremo Sul Catarinense Departamento de Medicina Criciúma SC | |
关键词: Hepatitis B virus; Vaccination; Anti-HBs; Anti-HBc; HBsAg; Vírus da hepatite B; Vacinação; Anti-HBS; Anti-HBc; HBsAg; | |
DOI : 10.1590/S0037-86822012000200024 | |
来源: SciELO | |
【 摘 要 】
INTRODUCTION: It is known that the hepatitis B (HB) vaccine is effective, but it is alarming that sudden drops of antibody levels may coincide with the onset of adolescence. METHODS: Antibody levels against HB vaccine surface antigen (anti-HBs) and HB vaccine core antigen (anti-HBc) were measured on the blood samples of children with a mean age of 11.4 years. RESULTS: About 54.8% had protective levels of anti-HBs. Of those who were anti-HBc-positive (4.4%), an average of 218.4 anti-HBs mIU/mL was found. CONCLUSIONS: Immunological protection was found in the majority of children. However, more studies are needed to elucidate the heritability of nonresponders and establish strategies against such events.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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