Hepatitis B virus infection on male partner has negative impact on in-vitro fertilization

1st International Conference on Tropical Medicine and Infectious Diseases (ICTROMI) Faculty of Medicine Universitas Sumatera Utara

Lubis, H.P.^1 ; Halim, B.^1 ; Adenin, I.^1 ; Rusda, M.^1 ; Prasetiawan, E.^1

HFC IVF Center, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sumatera Utara, Haji Adam Malik General Hospital, Medan, Indonesia^1

关键词: Control groups;    Hepatitis B virus;    Hepatitis B virus infection;    In-vitro;    Medical center;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/125/1/012045/pdf
DOI  :  10.1088/1755-1315/125/1/012045

来源: IOP

【 摘 要 】

It is common to see HBV-infected couple seeking for fertility treatment in reproductive medical centers. The effect of hepatitis B virus (HBV) infection on pregnancy outcome after In Vitro Fertilization (IVF) treatment has been a controversy. The study aims this was to evaluate the outcome of in vitro fertilization in couples with the male partner being HBsAg-seropositive. A retrospective analytic study was in HBV-infected and non-HBV infected male partner groups who have been treated with in vitro fertilization (IVF) from October 2016 until May 2017 in HFC IVF Center. From 101 couples, 17 (16.83%) male partners were HBV seropositive. They had similar semen parameters compared to thenon-HBV infected group. Couples with the male partner being HBsAg-seropositive had significantly lower fertilized oocytes and cleaved embryos compared to thenon-HBV infected group. We also found lower clinical pregnancy rate in infected male partner group compared to control group (23.52% vs 51% respectively). Statistically, there was a significant difference in clinical pregnancy rate between HBV-infected group and control group (p