Revista da Sociedade Brasileira de Medicina Tropical | |
Antibody levels in children after 10 years of vaccination against hepatitis B: a brazilian community-based study | |
Fagundes, Glauco Danielle1  Silva, Jane da1  Universidade do Sul de Santa Catarina, Palhoça1  Tabalipa, Fábio de Oliveira1  Universidade do Extremo Sul Catarinense, Criciúma1  | |
关键词: Hepatitis B virus; Vaccination; Anti-HBs; Anti-HBc; HBsAg; | |
DOI : 10.1590/S0037-86822012000200024 | |
学科分类:农业科学(综合) | |
来源: Sociedade Brasileira de Medicina Tropical | |
【 摘 要 】
INTRODUCTION: It is known that the hepatitis B (HB) vaccine is effective, but it is alarming that sudden drops of antibody levels may coincide with the onset of adolescence.METHODS: Antibody levels against HB vaccine surface antigen (anti-HBs) and HB vaccine core antigen (anti-HBc) were measured on the blood samples of children with a mean age of 11.4 years.RESULTS: About 54.8% had protective levels of anti-HBs. Of those who were anti-HBc-positive (4.4%), an average of 218.4 anti-HBs mIU/mL was found.CONCLUSIONS: Immunological protection was found in the majority of children. However, more studies are needed to elucidate the heritability of nonresponders and establish strategies against such events.
【 授权许可】
Unknown
【 预 览 】
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RO201912010167573ZK.pdf | 603KB | download |