Intestinal nematodes and pulmonary tuberculosis

Revista da Sociedade Brasileira de Medicina Tropical

Ricardo Tristão-sá¹  Rodrigo Ribeiro-rodrigues¹  Luciléia T. Johnson¹  Fausto Edmundo L. Pereira¹  Reynaldo Dietze¹ 

[1] ,Universidade Federal do Espírito Santo Centro Biomédico Núcleo de Doenças InfecciosasVitória ES ,Brazil

关键词: Tuberculosis;    Helminthiasis;    Strongyloidiasis;    Mycobacterium tuberculosis;    Tuberculose;    Helmintíases;    Estrongiloidíase;    Mycobacterium tuberculosis;   

DOI  :  10.1590/S0037-86822002000500020

来源: SciELO

【 摘 要 】

We report a significantly higher prevalence of intestinal nematodes in patients with pulmonary tuberculosis (TB) compared to a matched control group: 33/57 (57.8%) in patients with TB and 18/86 (20.9%) in the control group; OR=5.19; 95% CI= 2.33-11.69; p=0.000). When TB patients eosinophilia was also significantly higher among those with intestinal parasites (69.8%) compared to those without this condition (45.6%). We hypothesized that the immune modulation induced by nematodes is a factor that enhances TB infection/progression and that eosinophilia seen in TB patients is a consequence of helminth infection.

【 授权许可】

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