HEPATOCELLULAR CARCINOMA IN A NON-CIRRHOTIC PATIENT WITH SUSTAINED VIROLOGICAL RESPONSE AFTER HEPATITIS C TREATMENT

Revista do Instituto de Medicina Tropical de São Paulo

Angelo Alves De Mattos¹  Patrícia Dos Santos Marcon¹  Fernanda Schild Branco De AraÚjo¹  Gabriela Perdomo Coral¹  Cristiane Valle Tovo¹ 

关键词: Hepatocellular carcinoma;    Hepatitis C;    Genotype 3;    Sustained virological response;    Non-cirrhotic liver;   

DOI  :  10.1590/S0036-46652015000600011

来源: SciELO

【 摘 要 】

Chronic infection by hepatitis C virus (HCV) is one of the main risk factors for the development of liver cirrhosis and hepatocellular carcinoma. However, the emergence of hepatocellular carcinoma (HCC) in non-cirrhotic HCV patients, especially after sustained virological response (SVR) is an unusual event. Recently, it has been suggested that HCV genotype 3 may have a particular oncogenic mechanism, but the factors involved in these cases as well as the profile of these patients are still not fully understood. Thus, we present the case of a non-cirrhotic fifty-year-old male with HCV infection, genotype 3a, who developed HCC two years after treatment with pegylated-interferon and ribavirin, with SVR, in Brazil.

【 授权许可】

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