Botulism in Brazil, 2000-2008: epidemiology, clinical findings and laboratorial diagnosis

Revista do Instituto de Medicina Tropical de São Paulo

Ruth Estela Gravato Rowlands²  Christiane Asturiano Ristori²  Giselle Ibette S. Lopez Lopes²  Ana Maria Ramalho De Paula²  Harumi Sakuma²  Raquel Grigaliunas²  Roberto Lopreato Filho²  Dilma Scala Gelli²  Maria Bernadete De Paula Eduardo¹  Miyoko Jakabi² 

[1] ,Adolfo Lutz Institute Food Microbiology Laboratory São Paulo SP ,Brazil

关键词: Botulism;    Botulinum neurotoxin;    Clostridium botulinum;    Laboratorial diagnosis;    Epidemiologic surveillance;   

DOI  :  10.1590/S0036-46652010000400003

来源: SciELO

【 摘 要 】

Botulism is a rare and potentially lethal illness caused by Clostridium botulinum neurotoxin. We describe the findings of a laboratorial investigation of 117 suspected cases of botulism reported to the surveillance system in Brazil from January 2000 to October 2008. Data on the number and type of samples analyzed, type of toxins identified, reporting of the number of botulism cases and transmission sources are discussed. A total of 193 clinical samples and 81 food samples were analyzed for detection and identification of the botulism neurotoxin. Among the clinical samples, 22 (11.4%) presented the toxin (nine type A, five type AB and eight with an unidentified type); in food samples, eight (9.9%) were positive for the toxin (five type A, one type AB and two with an unidentified type). Of the 38 cases of suspected botulism in Brazil, 27 were confirmed by a mouse bioassay. Laboratorial botulism diagnosis is an important procedure to elucidate cases, especially food-borne botulism, to confirm clinical diagnosis and to identify toxins in food, helping sanitary control measures.

【 授权许可】

CC BY-NC   
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