Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination

Revista do Instituto de Medicina Tropical de São Paulo

Manuel Mindlin Lafer¹  Maria Isabel De Moraes-pinto¹  Lily Yin Weckx¹ 

[1] ,Federal University of São Paulo Division of Pediatric Infectious Diseases São Paulo SP ,Brazil

关键词: Varicella Zoster;    Antibodies;    Brazilian native Indians;   

DOI  :  10.1590/S0036-46652005000300004

来源: SciELO

【 摘 要 】

The purpose of the study was to estimate the prevalence of IgG antibodies against varicella zoster virus (VZV) in the two most populated indigenous ethnic groups from Xingu Indigenous National Park, in Brazil, prior to the introduction of vaccination against the disease, and to determine the positive and the negative predictive values of a history of varicella infection. In 2001, 589 inhabitants of two Kuikuro villages and three Kaiabi villages were evaluated and provided information concerning previous varicella infection. An indirect immunosorbent assay (ELISA) to detect IgG anti-VZV antibodies was performed in 224 blood samples - volunteer selection had no interference of anamnesis. IgG prevalence was 80.8% (95% Confidence Interval: 76% - 86%). The seroepidemiology of varicella in Xingu National Park prior to varicella vaccine introduction was comparable to the Brazilian national seroprevalence described in the literature, and so were the positive (98%) and the negative predictive value (41%) of the referred history.

【 授权许可】

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