Evidences against a significant role of Mus musculus as natural host for Angiostrongylus costaricensis

Revista do Instituto de Medicina Tropical de São Paulo

Fernanda Teixeira Dos Santos¹  Viviane M. Pinto¹  Carlos Graeff-teixeira¹ 

[1] ,PUCRS Inslitulo de Biociências Dept. Ciências Microbiológicas

关键词: Angiostrongylus costaricensis;    Mus musculus;    Angiostrongylosis;   

DOI  :  10.1590/S0036-46651996000300002

来源: SciELO

【 摘 要 】

Wild rodents have been described as the most important hosts for Angiostrongylus costaricensis in Central America and southern Brazil. Sinantropic rodents apparently do not play a significant role as natural hosts. A search for natural infection failed to document worms in 14 mice captured in the house of a patient with diagnosis of abdominal angiostrongylosis and experimental infection of a "wild" Mus musculus strain and groups of albino Swiss mice were carried out. Mortality was not significantly different and varied from 42% to 80% for Swiss mice and from 26% to 80% for "wild" mice. The high mortality of a "wild" M. musculus infected with A. costaricensis was very similar to what is observed with most laboratory mice strains. These data may be taken as indications that M. musculus is not a well adapted host for A. costaricensis, although susceptibility was apparently higher with "wild" populations of M. musculus as compared to Swiss strain.

【 授权许可】

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