Antioxidant Activity of Haramounting Leaf Ethanol Extract (Rhodomytrus tomentosa) In Preventing Heart Damage of Mice (Mus musculus L.) after exposure to Electronic Cigarette

4th International Conference on Biological Sciences and Biotechnology

Ilyas, S.^1 ; Tanjung, R.S.^1 ; Hutahaean, S.^1 ; Tanjung, M.^1^2 ; Elimasni^1 ; Jamilah, I.^1 ; Murdela, F.^1

Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, Indonesia^1

Center of Excellence for Natural Resources-Based Technology, Mangrove and Bio-Resources Group, Universitas Sumatera Utara, Medan, Indonesia^2

关键词: Anti-oxidant activities;    Block methods;    Cigarette smokes;    Completely randomized designs;    Ethanol extract;    Histological observations;    Liver cells;    Mus musculus;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/305/1/012080/pdf
DOI  :  10.1088/1755-1315/305/1/012080

来源: IOP

【 摘 要 】

Cigarette smoke is one factor that increases free radicals in the blood will affect liver health in the body. The purpose of this study is to find outthe effect of giving leaves ethanol extract haramounting to histology of male mice liver exposed to electric cigarettes. The design of this study used Completely Randomized Design (CRD) consisting of + Group, - Group and three treatments of Haramounting Leaf Ethanol Extract (Rhodomyrtus tomentosa (Aiton) Hassk.) for 30 days at a dose of 100 mg/kg BW Body Weight, 200 mg/kg BW and 300 mg/kg BW for treament use of five replications. Liver organ preparations were made using paraffin block method and Hematoxylin Erlich-Eosin (HE) staining. The results of the study show on histological observations The liver has a tendency that electric cigarette smoke can cause damage in liver cells. The results of this study indicate that ethanol extract leaves of Haramounting after exposure to eletric cigarette smoke can effectively regenerate damaged liver cells.