Prevalence of potentially reversible dementias in a dementia outpatient clinic of a tertiary university-affiliated hospital in Brazil

Arquivos de Neuro-Psiquiatria

Leonel Tadao Takada¹  Paulo Caramelli²  Marcia Radanovic²  Renato Anghinah¹  Ana Paula B. J. Hartmann¹  Carla Cristina Guariglia¹  Valéria Santoro Bahia¹  Ricardo Nitrini² 

[1] ,University of São Paulo School of Medicine Hospital das Clínicas Department of NeurologySão Paulo SP ,Brazil

关键词: dementia;    prevalence;    Alzheimer's disease;    neurosyphilis;    hydrocephalus;    demência;    prevalência;    doença de Alzheimer;    neurossífilis;    hidrocefalia;   

DOI  :  10.1590/S0004-282X2003000600007

来源: SciELO

【 摘 要 】

The importance of investigating the etiology for dementia lies in the possibility of treating potentially reversible dementias. The aims of this retrospective study are to determine the prevalence of potentially reversible dementias among 454 outpatients seen at the Cognitive and Behavioral Neurology Unit, Hospital das Clínicas, São Paulo University School of Medicine - Brazil, between the years of 1991 and 2001, and observe their evolution in follow-up. Among the initial 454 patients, 275 fulfilled the DSM-IV criteria for dementia. Alzheimer's disease was the most frequent diagnosis (164 cases; 59.6%). Twenty-two cases (8.0%) of potentially reversible dementia were observed, the most frequent diagnoses being neurosyphilis (nine cases) and hydrocephalus (six cases). Full recovery was observed in two patients and partial recovery in 10 patients. Two cases were not treated and eight cases were lost on follow-up. The prevalence found in the present study falls within the range reported in previous studies (0-30%).

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